Simon Hughes MP, business partners from the local Southwark community, as well as HawkinsBrown - the buildings architects - were in attendance.
Following speeches from Vice Chancellor Professor Martin Earwicker, Chancellor Richard Farleigh and Students' Union President Anisa Ali, the Centre was officially opened when a commemorative plaque was revealed.
Students and staff were then treated to an evening of fun, which included a barbeque, candy floss, ice cream, and special student displays and exhibitions.
The £7.42 million development offers a dynamic central location where students can easily access support services and find out more about employment opportunities, as well as providing a space where they can socialise and relax. HawkinsBrown's state of the art design of the building was shortlisted for a RIBA and a Design Week award.
LSBU's Vice-Chancellor Professor Martin Earwicker said: "We listened to our students throughout the planning process - from how they want to access support and careers services through to choosing colours at the design stage - so we're sure that this Centre will really enhance the student experience at our University.
"LSBU students now not only have an exciting new space to meet and to work in, but they also have quick and easy access to any support they need, and information on professional opportunities, such as mentoring and internships, at their fingertips."
The building was launched to students in November 2012, but the evening's ceremony marked the official opening.