Proteomics and Genomics
The Tutorial Programme
These present and integrate new material
that is not in the lectures. You will be grouped and each group will prepare
for one of the discussions before the tutorials.
- General revision, introduction
to the tutorial format and organisation of the class into groups for leading
the discussions
- “Is ‘Genomics’ ethical?” Discussion
- Has the human genome project delivered?
Discussion
- Protein structure-activity relationships;
further examples. Discussion of the question ‘Show how bab
motifs may be used in the construction of (a/b)8
barrels (“TIM barrels”) and Open Twisted Sheets. Comment on the major functional
role played by each of these structural elements’
- Enzyme engineering. Discussion
of the question ‘Set out a plan as to how you would attempt to redesign Aspergillus
glucoamylase to make it more thermostable. (The three-dimensional crystal
structure of this enzyme is known)’
- How important is water to the
structure and activity of proteins?
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This page was last updated by Martin Chaplin
on
30 August, 2004
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